Resume

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Education

  • Doctor of Philosophy, Duke University Program in Genetics & Genomics, May 2013
  • Bachelor of Science, University of Florida, Biochemistry Major, May 2008
  • Counseling & Education Experience

  • Assistant Director of Graduate Services, Career Center, Duke University, Durham, NC, January 2015-Present
  • Education Researcher, Freelance, September 2014-Present
  • Co-Founder, North Carolina Central University, Durham, NC, December 2013-January 2015
  • Teaching Experience

  • Instructor, Center for Science, Math, & Technology Education, North Carolina Central University, Durham, NC, August 2013-January 2015
  • Guest Lecturer, Biology Department, North Carolina Central University, Durham, NC, April 2014
  • Instructor, North Carolina Central University, Biology Department, Durham, NC, March 2014-April 2014
  • Guest Lecturer, Biology Department, North Carolina Central University, Durham, NC, March 2014
  • Instructor, Duke University Talent Identification Program, Winston-Salem, NC, July 2013
  • Guest Lecturer, Department of Molecular Genetics & Microbiology, Duke University, August 2012
  • Teaching Assistant, Duke University, August 2010-December 2010
  • Teaching Assistant, University of Florida, August 2005-December 2005, August 2006-December 2006
  • Classroom Volunteer, Newberry High School, September 2004-December 2004
  • Research Experience

  • HHMI Postdoctoral Fellow, Dr. Jodie Fleming’s Lab, North Carolina Central University, August 2013–January 2015
  • Graduate Student, Dr. Douglas Marchuk's Lab, Duke University, August 2008-May 2013
  • Undergraduate Researcher, InvestiGators, University of Florida, December 2004-May 2008
  • Laboratory and Computational Skills
  • Mentoring

  • Dionna Gamble, University of Maryland, Baltimore County Undergraduate, Summer 2013
  • Nicholas De Castro, Elon University Undergraduate, Summer 2012
  • Emily Ngan, Duke University Undergraduate, Summer 2012
  • Stephanie Li, Duke University Undergraduate, Fall 2009-Spring 2010
  • Honors & Awards
    Jhumki Basu Equity Scholars Award, International Conference of the National Association for Research in Science Teaching, March 2014

    Postdoctoral Travel Award, International Society for the Scholarship of Teaching and Learning, October 2013

    Third Place, National Science Foundation Innovation in Graduate Education Challenge, June 2013 - see Proposal and News Article

    Predoctoral Travel Award, Angioma Alliance, Pathobiology of CCM Scientific Workshop, November 2012

    National Research Service Award, National Institute of Neurological Disorders and Stroke, #F31NS077702, December 2011-May 2013 - see Specific Aims and Proposal

    Predoctoral Fellowship, American Heart Association, #11PRE7360003, July 2011-December 2011 - see Proposal

    Predoctoral Travel Award, Angioma Alliance, Pathobiology of CCM Scientific Workshop, November 2010

    James B. Duke Fellowship, Duke University, March 2008

    University Scholars Program, University of Florida, April 2006– May 2008

    Publications
    McDonald DA. PhD supervisors: invest more time. Nature 2017; 545(7653): 158. Download

    Reaves DK, Hoadley KA, Fagan-Solis KD, Jima DD, Bereman M, Thorpe L, Hicks J, McDonald D, Troester MA, Perou CM, Fleming JM. Nuclear localized LSR: a novel regulator of breast cancer behavior and tumorigenesis. Molecular Cancer Res 2017; 15(2): 165-78. Download

    Shenkar R, Shi C, Austin C, Moore T, Lightle R, Cao Y, Zhang L, Wu M, Zeineddine HA, Girard R, McDonald DA, Rorrer A, Gallione C, Pytel P, Liao JK, Marchuk DA, Awad IA. RhoA kinase inhibition with fasudil versus simvastatin in murine models of cerebral cavernous malformations. Stroke 2017; 48(1): 187-94. Download

    Bennett CL, Finch A, Vuong K, McDonald DA, Rennie S. Underreporting of duty hours – a national survey of general surgery residents. New England Journal of Medicine 2016; 374: 2399-403. Download

    McDonald DA. Tips for talking about other options. Inside Higher Ed 2016.

    McDonald DA, Marchuk DA. The Roles of KRIT1, Malcavernin (CCM2), and PDCD10 in the Pathogenesis of Cerebral Cavernous Malformations. Epstein’s Inborn Errors of Development, 3rd Edition. Erickson B, Wynshaw-Boris T, eds. 2016.

    McDonald DA, Council SE, Schroeder SC, Utile S, Phillips RS, Hollowell GP, Key SCS. Identifying promoter activators and repressors using lacZ transgene expression in Saccharomyces cerevisiae. Association for Biology Laboratory Education 2015; 37. Download

    Shenkar R, Shi C, Rebeiz T, Stockton R, McDonald DA, Mikati A, Zhang L, Austin C, Akers AL, Gallione CJ, Rorrer A, Gunel M, Min W, Marcondes J, Lee C, Marchuk DA, Awad IA. Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. Genetics in Medicine 2015; 17(3); 188-96. Download

    McDonald DA, Shi C, Shenkar R, Gallione CJ, Akers AL, Li S, de Castro N, Berg MJ, Corcoran DL, Awad IA, Marchuk DA. Lesions from sporadic cases of cerebral cavernous malformations harbor somatic mutations in the CCM genes: Evidence for a common biochemical pathway for CCM pathogenesis. Human Molecular Genetics 2014; 23(16): 4357-70. Download

    McDonald DA, Shi C, Shenkar R, Stockton RA, Liu F, Ginsberg MH, Marchuk DA, Awad IA. Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. Stroke 2012;43(2):571-4. Download

    McDonald DA, Shenkar R, Shi C, Stockton RA, Akers AL, Kucherlapati MH, Kucherlapati R, Brainer J, Ginsberg MH, Awad IA, Marchuk DA. A novel mouse model of cerebral cavernous malformations based on the two-hit hypothesis recapitulates the human disease. Hum Molec Genet 2011;20(2): 211-22. Download

    Jones LL, McDonald DA, Borum PR. Acylcarnitines: role in brain. Prog Lipid Res 2010;49(1):61-75. Download

    Quoted & Featured
    Roth B. 3 Steps to Reach Your Professional Potential. Working@Duke 2017.

    What Else Can I Do With My PhD? Duke Clinical and Translational Science Institute 2016.

    Presentations
    McDonald DA. Assessment for beginners. Oral presentation, OneDuke Conference, May 2017.

    Council SE, Grillo WH, Key SCS, Royal MO, McDonald DA, Phillips RS, Hollowell GP, White SL. Development and infusion of course-based undergraduate research experiences (CUREs) into introductory core courses of a biology curriculum. American Society for Microbiology Conference for Undergraduate Educators, May 2015. Abstract

    Shenkar R, Shi C, McDonald DA, Austin C, Rorrer A, Gallione CJ, Zhang L, Marchuk DA, Awad IA. A comparison between fasudil and simvastatin treatment in two murine models with cerebral cavernous malformation. Poster, International Stroke Conference, February 2015.

    Hollowell GP, Grillo WH, Key SCS, Phillips RS, Royal MO, Council SE, McDonald DA, White SL. Improving student retention: course based undergraduate research experiences for biology majors. Poster, Association of American Colleges and Universities. Diversity, Learning, and Student Success Meeting, March 2014. Download

    Grillo WH, Hollowell GP, Key SCS, Phillips RS, Royal MO, Council SE, McDonald DA, White SL. Development and infusion of course-based undergraduate research experiences (CUREs) into introductory core courses of a biology curriculum. Poster, CUREnet Meeting, March 2014.

    Gamble D*, Gallione CJ, McDonald DA, North P, Marchuk DA. Somatic mutations leading to vascular anomalies: is the GNAQ somatic mutation the link? Poster, Annual Biomedical Research Conference for Minority Students, November 2013.

    McDonald DA, Shenkar R, Shi C, Awad IA, Marchuk DA. Exploring the implications of a two-hit mechanism in cerebral cavernous malformations. Oral presentation, Pathobiology of CCM Scientific Workshop, November 2012.

    McDonald DA, Shi C, Shenkar R, Stockton RA, Liu F, Ginsberg MH, Marchuk DA, Awad IA. Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease. Oral presentation, Pathobiology of CCM Scientific Workshop, November 2011.

    McDonald DA, Shenkar R, Shi C, Akers AL, Stockton RA, Kucherlapati M, Kucherlapati R, Ginsberg MH, Awad IA, Marchuk DA. A second-generation mouse model to study cerebral cavernous malformations lesion development. Poster, American Society for Human Genetics. Annual Meeting, November 2010. Download

    McDonald DA, Shenkar R, Shi C, Akers AL, Stockton RA, Kucherlapati M, Kucherlapati R, Ginsberg MH, Awad IA, Marchuk DA. A second-generation mouse model to study cerebral cavernous malformations lesion development. Angioma Alliance. Oral presentation, Pathobiology of CCM Scientific Workshop, November 2010.

    McDonald DA, Akers AL, Kucherlapati R, Kucherlapati M, Shenkar R, Shi C, Awad IA, Marchuk DA. A second-generation mouse model of cerebral cavernous malformation pathogenesis. North American Vascular Biology Organization. Poster, Genetics and Genomics of Vascular Disease Workshop, September 2009. Download

    McDonald DA, Borum PR. Sex steroid hormones affect carnitine concentrations of blood and organs in rats. Poster, Experimental Biology, April 2008. Download

    McDonald DA, Borum PR. Effects of chemical diabetes and starvation on blood and organ carnitine concentrations in rats. Poster, Experimental Biology, April 2007. Download

    Service
    Student Affairs Assessment Task Force, Duke University, September 2016-Present

    Member, Graduate Student Affairs Advisory Committee, September 2016-Present

    Reviewer, HHMI Biointeractive, August 2014-January 2015

    Reviewer, European Journal of Human Genetics, June 2014

    Founding Member, North Carolina Central University Postdoc Association, December 2013-January 2015

    Duke Reader Project, Duke University, August 2013-June 2015

    Instructor, North Carolina DNA Day, April 2013

    Science Fair Judge, North Carolina Student Academy of Science, March 2013

    Scholar, Duke Scholars in Cardiovascular Medicine, August 2012-May 2013

    Reviewer, Syllabus Journal, July 2012-May 2013

    Preparing Future Faculty Program, Duke University, August 2011–July 2012

    Memberships
    Member, Graduate Career Consortium, March 2015-Present

    Member, National Association of Colleges and Employers, March 2015-Present

    Member, National Association for Research in Science Teaching, December 2013 – Present

    Professional Development
    National Conference, Graduate Career Consortium, June 2017

    Assessment Conference, North Carolina Independent Colleges & Universities, June 2017

    Career Development for Biomedical Scientists, National Institutes of Health, July 2016

    Intercultural Skills Development Program, Duke International House, May 2016

    National Conference, National Association of Colleges and Employers, June 2015